How does Sibutril work?

Neurotransmitters are the chemicals that are found in the brain. These are produced by the nerves or neurons and released in order to communicate with other nerves or neurons. These released nerves binds with the other nerves and they are again taken up by the nerves which releases them. So this cycle is called reuptake. So when you take Sibutril, it stops the reuptake of neurotransmitters like serotonin,dopamineor norepinephrine. Inhibition of neurotransmitterreuptake changes the balance of neurotransmitters within the cells of the nerves. Thus it impact on the nerve function and their interactions.

What are the indications of Sibutril?

• Sibutril is used for the treatment of obesity or overweight. This medication is best effective in combination of a low calorie diet in patient only whose body mass is above 30kg/m2.
• This medication can safely be used in the person who has high cholesterol, high blood pressure and diabetes.

What is the dose of Sibutril?

The most recommended dose of this medication is 10mg, once in a day. However, depending on the tolerability, the strength of the dose can be decreased to 5mg or increased up to 15mg, once in a day. Your physician will always give priorities in checking blood pressure and heart rate before prescribing this medication to you.

What are the contraindications of Sibutril?

Like other medication, this medication also exhibits some contra-indications like,

• In uncontrolled blood pressure.
• If the person is allergic to any components of the medication.
• In the patient who has a history of alcohol abuse.
• In heart diseases such as coronary artery diseases, tachycardia, congestive heart failure, cardiac arrhythmias, cerebrovascular disease or congestive heart disease.
• If you have a history of pulmonary hypertension.
• In hyperthyroidism.
• In a man who suffers from diseases related to prostate gland.
• It is not used in pregnant and lactating women.
• This medication is not indicated under the age of 18 years and above 65 years.

What are the drug interactions of Sibutril?

This medication has some significant drug interactions, such as:

• This medication can interact with monoamine oxidase inhibitors (MOA) and may lead to serotonin syndrome which is a very rare condition. So Sibutrin is always avoided to take within two weeks of pausing or beginning any MAOI.
• Opiods should also be avoided in concomitant use with Sibutril.
•  It can also interact with ergolines and triptans.
• Concomitant use of some drugs like ketoconazole, erythromycin with Sibutril can increase plasma levels of Sibutramine.
• This medication cannot impact the hormonal contraception.

What are the side effects of Sibutril?

This medication has the following side effects like,

1. This medication should be avoided in the patients suffering from heart diseases, because it stimulates the risk of heart attack and strokes.
2. You can catch some common symptoms like dry mouth, nausea, change of the taste in mouth, stomach problem, disturbed sleep, dizziness or constipation.
3. Headache, muscle or bone pain or menstrual cramps.
4. This can increase the blood pressure. So the patient requires close monitoring.
5. Infrequent but serious side effects like mood swing, cardiac arrhythmias or depression.
6. Serious side effects which require immediate medical attention are convulsion, problem in urination, melena (black or dark stool), fevers with rigors, vision problem, sleeping disturbance and edema.

How should be stored Sibutril?

This medication should be stored in between the temperature of 15-30 degree Celsius, in a light resistant container. It should be stored in a dry place, away from the children.

What should be done if you miss a dose?

If you miss a dose, you should take the medication as soon as remember it. But always avoid to take the medication near the time of the next dose, because a double dose may cause serious complication for your health.

What are the precautions you should forSibutril?

1. Sibutramine can lead to dizziness or vision problem. The condition becomes worse if you take the medication with alcohol. So always avoid going out alone or driving vehicles after consuming this medication.
2. To achieve the ideal weight, it is important to follow a balance diet with proper exercise. So you should always follow the instruction and guideline given by your doctor while you are this medication.
3. You should always consult with your physician before taking this medication if you are under some drugs like MAO (monoamono oxidase inhibitors), some antipsychotics. Because such medication can cause serotonin syndrome which can be fatal for you. Some of the symptoms of this syndrome are agitation, increased blood pressure, nausea and vomiting, diarrhea, muscle rigidity, coma or hallucination. So if you catch any of the symptoms, contact your doctor without any delay.
4. You should always use an effective method of birth control while you are taking this medication.
5. Elderly people are more sensitive to the effects of this medication, so always use this medication with cautious in this people.
6. This medication is not in below the age of 18 years and above the age of 65 years.
7. You should always take this medication in pregnancy with cautious and proper consultation with your doctor.