How does Neomercazole work in your body?

Neomercazole is a widely used and effective antithyroid drug.It is available at two strengths, 5mg and 20mg.However, mechanism of action of Neomercazole is still not clear.The researchers presumed that Neomercazole acts by pausing the iodization of the tyrocyl residues in thyroglobulin. Chemical iodine is very important to the thyroid gland for the production of thyroid hormones.So, before iodine is used, it requires to get converted into a usable form.This is the most important point where Neomercazole starts working in the process.It lower the uptake and the lebel of inorganic iodine by thyroid. It means, at this point, Neomrcazole stops the convertion of iodine into its usable form.As a result, thyroid hormone production is reduced and helps in the treatment of hyperthyroidism.
Indications of Neomercazol:
The active ingredient of neomrcazole is Carbimazole. Since, Carbimazole is a potent components, it can be used as following:

• Neomercazole is widely used for the treatment of hyperthyroidism. It helps by reducing the production of thyroid hormones T3 and T4 by the thyroid gland.
• It can safely be used along with other medications.
• Neomercazole can be used before the partial surgical removal of thyroid gland to restore the normal activity of thyroid.
• Neomercazole is used post radio-active treatment of thyroid gland.

What are the Drug interactions of Neomerazole ?

Since, carbimazole is the active component, it has a tendency to interact with other drugs, such as:

• Neomercazole can interacts with cortcosteroids and can affect on the functions of corticosteroids.
• Neomercazole can interact with the antihypertensive like digoxin, so always use this drug with a adjusted dose of digoxin.
• Neomercazole has a tendency to react with theophylllines. It can increase the toxicity of theophylline. 

Dietary interaction with Neomercazole:

• Neomercazole can interact with the foods whic are rich in iodine like fish, soybased food.

Diseaese interaction with Neomercazole:

• Neomercazole can lead to many complication if you are sufferting any underlying disease. So always prefer to consult with your doctor before starting a dose of Neomercazole.

What are the Side effects of Neomercazole ?

Neomercazole has the following side effects:

• The patient who take Neomercazole, may develop agranulocytosis. Agranulocytosis indicates the failure of bone marrow to produce enough amount of white blood cells. Agranulocytosis is an idiosyncratic reaction that subsides after discontinuation of the Neomercazole.
• Agranulocytopenia is the one more side effect seen in a patient who use Neomercazole.Agranulocytopenia is a codition where a patient develop acute and severe leukopenia by lowering the concentration of white blood cells. The patient suffering from from agranucytopenia has a tendency to get infections because their immune system become very poor.
• The patient who take Neomercazole, may develop aplastic aneamia. Aplastic aneamia is a blood disorder, where body cannot produce new blood cells.
• Peripheral neuritis is one more side effect of Neomercazole. Peripheral neuritis is a condition when the patient has peripheral nerve infection.
• Neomercazole can also has the ability to cross the placental barrier and can secretes in the breast milk. So it should be avoided in the pregnancy and lactation period.

Other possible side effects are:

• Ulcers in the mouth
• High fever
• Tiredness
• Easy bruishing or tendency of bleeding
• Feeling of un-wellness
• Muscle and bone pain
• Yellowish discoloration of your skin or eyes(it occurs as a result of liver problem and may lead to jaundice) 

Note: Always be cautious for any of the side effect and consult with your doctor because he may suggest for some blood test to rule out the cause.

What are the Contraindication of Neomercazol ?

Neomercazole is contraindicated,

• If you are allergic to Neomercazole or any other components of the drug.
• Always avoid Neomercazole if the package of Neomercazole shows any damage or tempering signs.
• Do not use Neomercazole if it is expired or outdated. Because, an outdated Neomercazole may not give any result.
• Before start a dose of Neomercazole, always take a suggestion from your physician.
• Do not use Neomercazole if you are pregnant or planning for that.
• Do not use Neomercazole if you have any liver problem.
• Always take advice before taking Neomercazole if you have any blood disorder.

What are the Dosage of Neomercazole:

• Neomercazoole is available at the strength of 5mg and 20mg. 
• Always take Neomercazole according to your doctor's insatructions, because your doctor only can give you the accurate dose.
• Dosage of Neomercazole depends on the severity of the disease and the age of the patient.
• Dose can be changed with intervals.

Steps taking before you take Neomercazole 5mg and 20mg:

• Always read carefully the leaflet before taking Neomercazole.
• Ask your doctor if you have any confusion in taking the drug.
• Do not pass the tablets of Neomercazole to others. It may cause serious complication to them because they may have same symptoms like you, but may have other disease.
• If you see any unusual side effect, consult immediately with your doctor.

If you forget a dose of Neomercazole:

• If you forget any dose of Neomercazol 5mg or 20mg, you should take the next dose immediately as soon as you remember. 
• In case, if your next dose is on due, take both the doses together.
• Always clarify your doubts about the doses with your doctor. 

How to Store  Neomercazole:

• Always keep Neomercazole out of reach of children.
• Do not use expired Neomercazole.
• Do not store Neomercazole Above the temprature of 25 degree.
• If you need to discontinue the treatment with Neomercazole, always take the left out tablets of Neomercazole back to the pharmacy or chemist.
• Do not used any discolored or damaged tablets of Neomercazole.
• Should always dispose the unused tablets via wastewater.

What are the Precautions and warnings for Neomercazole

• Do not take Neomercazole if you are allergic to carbimazole or any other components of this drug.
• Always avoid Neomercazole if you are pregnant.
• Stop using the drug if you develop any blood related problem.
• Stop taking Neomercazole if you notice color changes of your skin and the eyes.
• Always take the advice of your doctor if you develop any of the side effects.