How doesAvagra 100 Works?

Avanafil is a selective inhibitor of PDE5 (phosphodiesterase type-5) group. So this medication inhibits an enzyme called phosphodiesterase type 5 that is present in the spongy tissues called corpus covernosum. According to the researchers, the drug has been proved very good in men who are facing the problem of ED and allows them to enjoy the sexual activity only in 15 minutes after oral intake. When the person suffering from ED takes this drug, it starts working by increasing the blood flow to the male genital organ and inhibits the output of the blood flow. It increases the synthesis of the nitric oxide and cyclic guanosine monophosphate (cGMP).These are responsible for the smooth muscle relaxation which causes erection. When the cGMP is degraded by some other enzyme, phosphodiesterase-5, the arteries return back to normal size, blood flows out of the penis, and it ends the erection. So this medication inhibits phosphodiesterase-5 from breaking down cGMP to make it stay longer.

What is the indication of Avagra 100?

Avagra 100 is a PDE-5 inhibitor, is indicated for the treatment of erection dysfunction in men.

What are the contraindications of Avagra 100?

Some of the contraindications of Avagra 100mg are:

• If you are allergic to Avanafil or any other ingredient of the medications.
• It cannot be used under the age of 18 years.
• This medication is not used in breastfeeding and pregnant women.
• Any liver disease like cirrhosis, liver failure or hepatitis.
• If you are suffering from any disease related to kidney.
• If you are experiencing any cardiac disorders like heart attacks, strokes, coronary heart disease, angina or chest pain, heart failure, aortic stenosis, high or low blood pressure etc.
• Any blood disorder like multiple myeloma, sickle cell anaemia or leukaemia.
• If you have any blood related problems like retinitis pigmentosa, blurred vision or colour blindness.
• Congenital anomaly of the penis.
• If you are under any hypertensive drugs.

What are the drug interactions of Avagra 100?

Since Avagra has the same potency like Viagra, so it has the similar drug interactions. Some of the drug interactions of Avagra are:

• Cisapride.
• Methscopolamine nitrate.
• Nitrates like amyl nitrite, isosorbidedinitrate, isosorbidemononitrate or nitroglycerin.
• Nitroprusside.
• Drugs for hypertension or high blood pressure.
• Drugs for the treatment of HIV infection or AIDS.
• Some medications used for fungal or yeast infections, like fluconazole, itraconazole, ketoconazole, and voriconazole.
• Cimetidine.
• Erythromycin, Clarithromycin or telithromycin.
• Anti-tuberculosis like rifampin or thiocetazone.

What are the side effects of Avagra 100?

Some of the possible side effects of Avagra 100 are:

• Facial flushing
• Headache
• Runny nose
• Back pain
• Sore throat

Some severe but rare side effects are:

• Priapism (Erection lasting for more than four hours)
• Sudden vision loss

Note: If you catch any serious problem which bothers your health, discontinue the medication and consult with your physician to avoid the complications.

How to use Avagra 100?

The most recommended dose of Avagra for adults is 100 mg per day. This dose of this medication should be taken minimum 30 minutes before the planned physical intercourse.This medication absorbs very fast in your body and gives an effective result within 15 minutes. Depending on the effectiveness and tolerability, the dose can be reduced to 50 mg and increased up to 200 mg. You should not take more than one tablet in 24 hours. You can take the medication with or without food.

What should you do if you take an overdose of Avagra 100?

Taking this medication more than the recommended dose, may cause serious complications. Always ask for medical assistance if you take an overdose as early as possible.

How should you store Avagra 100?

Do not store this medication below the temperature of 30 degree Celsius. Always dispose the unused and expired tablets. You can keep it in the refrigerator, but never freeze it. Always keep the medication out of reach of children.

What are the precautions you should take for Avagra 100?

• If you catch any eye problem while taking this medication, talk to your physician immediately.
• If the erection lasts for more than 4 hours or the erection is painful,inform your doctor as early as possible.Because it can cause serious complications if it is not treated in the right time.
• Discontinue this drug and talk to your health care provider immediately if you develop any symptoms like nausea, dizziness, chest pain or arm pain after taking this medication.
• It is not recommended to take this medication if you are under any nitrite containing medication. Because the combination these two medication may cause sudden drop in blood pressure.
• Discontinue this drug if you catch any breathing difficulty and inform your doctor as early as possible.
• Consult with your doctor if you catch any swelling on your face, lips or tongue.
• This medication is not recommended for the use below the age of 18 years.

Avagra 100 is not indicated in women and children.