Mechanism of action of Dostinex 0.25mg:

The anterior pituitary secretes the prolactin hormone which is controlled by the hypothalamic inhibitory control. The active ingredient of Dostinex is cabergoline which is a long-acting dopamine dopamine receptor agonist. Cabergoline has a strong affinity for D2 receptors. So this medication works by the following activities:

• It stops the release of prolactin from the pituitary gland.
• It exhibits the minimum affinity towards dopamine D1, alpha1 and alpha2- adrenergic receptors as well as 5-HT1 and 5-HT2 serotonin receptors.

Indications of Dostinex 0.25mg:

This medication is used to manage hyperprolactinemic diseases that may be idiopathic or due to the adenomas of pituitary gland.

Possible side effects of dostinex 0.25mg:

After doing research on many hyperprolactinemic patients, the scientists say that cabergoline or Dostinex 0.25mg shows very rare side effects that are mild to moderate in intensity. Always take this medication only after consulting with your doctor, because your doctor only can judge whether you are fit for this medication or not. Some of the possible side effects of this medication are:

Common side effects:

• Nausea and vomiting
• Constipation
• Dizziness
• Light headedness
• Tiredness
• Stomach upset

Serious side effects:

• Shortness of breath
• Tiredness
• Nervousness
• Mood changes
• Cough
• Vision problem
• Tenderness of breast
• Painful menstruation
• Swelling of your ankle and feet

Emergency side effects:

• Back pain
• Change in the urine concentration
• Chest pain

Very rare and serious allergic reaction:

• Itching or swelling of the face, throat or tongue
• Dizziness
• Trouble in breathing
• Skin rash

The above mentioned list is not a complete list of all the possible side effects. So, if you notice any other symptoms during the use of this medication, contact your physician or pharmacist.

Possible drug interactions of Dostinex 0.25mg:

It is not possible to mention all the possible drug interaction of this medication. We suggest you to inform your doctor if you are taking any other medication. Some of the drugs names are mentioned below:

• Metoclopramide
• Thioxanthenes
• Butyrophenones
• Phenothiazines

Overdose of this medication:

Always take this medication as per your doctor’s instruction. Because excessive or overdose can cause syncope, hallucination and nasal congestion. Monitor your blood pressure regularly while taking this medication.

Dosage of Dostinex:

This medication should be taken only twice in a week.

Precautions and contraindications associated to this medication:

If you are taking Cabergoline or Dostinex 0.25mg, you should always take the following precautions, such as:

• Avoid this medication if you are allergic to Cabergoline or other ingredient of this medication.
• Inform your physician if you are hypersensitive to any other medication.
• Tell your health care provider if you are suffering any other medical conditions like liver disorder, renal problem, increased blood pressure, Lung disease, abdominal problem and cardiac disease.
• This medication can make you feel dizziness. So avoid driving vehicle, or any activities that need mental alertness.
• Avoid alcoholic beverages.
• Inform your physician if you are taking other drugs like herbal, vitamins, mineral products and also prescribed and non-prescribed drugs.
• This medication is not indicated in pregnant women or if planning for pregnancy.
• Cabergoline secretes in breast milk. So this drug is not recommended in lactating women.
• Patients experiencing any cardiovascular disease should consult with their health care provider before taking this medication.